Spirometry in 5-year-olds-validation of current guidelines and the relation with asthma.

Pediatr Pulmonol. 2007 Dec;42(12):1144-51.
Turner SW, Craig LC, Harbour PJ, Forbes SH, McNeill G, Seaton A, Devereux G, Helms PJ.
Department of Child Health, University of Aberdeen, Aberdeen, UK.

Introduction. Spirometry is more frequently measured in younger children. Our primary aim was to validate 2005 ATS-ERS Task Force standards for spirometry in adults and older children among a population of 5-year-old children. Our secondary aim was to relate spirometry to asthma symptoms

METHODS: Children were participants in a longitudinal cohort study where asthma symptoms and spirometry were assessed.

RESULTS: Of the 827 children assessed, spirometry was obtained in 638 (85 with wheeze). A back-extrapolated volume/FVC ratio of <5% was achieved in 99% of children, the best two FVC were /=3 sec, whereas 80% had an FET of >/=1 sec. All criteria (including FET >/=1 s and FVC

CONCLUSIONS: The standards for spirometry are mostly achieved in this age group but are not necessarily valid and require revision. Reliable spirometry is feasible in 5-year-old children where reduced measurements are associated with asthma symptoms and in whom FEF(50) appears to be the most discriminatory variable.




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